Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain

Osteoarthritis (OA) is a painful and debilitating disease. A striking feature of OA is the dramatic increase in vascular endothelial growth factor (VEGF) levels and in new blood vessel formation in the joints, both of which correlate with the severity of OA pain. Our aim was to determine whether ant...

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Pubblicato in:Gene Rep
Autori principali: Das, Vaskar, Kc, Ranjan, Li, Xin, O-Sullivan, InSug, van Wijnen, Andre J., Kroin, Jeffrey S., Pytowski, Bronislaw, Applegate, Daniel T., Votta-Velis, Gina, Ripper, Richard L, Park, Thomas J, Im, Hee-Jeong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411090/
https://ncbi.nlm.nih.gov/pubmed/30873504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.genrep.2018.03.008
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