Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain

Osteoarthritis (OA) is a painful and debilitating disease. A striking feature of OA is the dramatic increase in vascular endothelial growth factor (VEGF) levels and in new blood vessel formation in the joints, both of which correlate with the severity of OA pain. Our aim was to determine whether ant...

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Udgivet i:Gene Rep
Main Authors: Das, Vaskar, Kc, Ranjan, Li, Xin, O-Sullivan, InSug, van Wijnen, Andre J., Kroin, Jeffrey S., Pytowski, Bronislaw, Applegate, Daniel T., Votta-Velis, Gina, Ripper, Richard L, Park, Thomas J, Im, Hee-Jeong
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411090/
https://ncbi.nlm.nih.gov/pubmed/30873504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.genrep.2018.03.008
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