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Anti-BCMA immunotoxins produce durable complete remissions in two mouse myeloma models
Multiple myeloma (MM) is a B cell malignancy for which new treatments are urgently needed. The B cell maturation antigen (BCMA) is a lineage-restricted differentiation protein highly expressed on myeloma. Recombinant immunotoxins (RITs) are proteins composed of the Fv or Fab portion of an antibody f...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6410834/ https://ncbi.nlm.nih.gov/pubmed/30782819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821733116 |
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