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Preclinical development of anti-BCMA immunotoxins targeting multiple myeloma
BACKGROUND: Multiple myeloma (MM) is a B-cell malignancy that is incurable for the majority of patients. New treatments are urgently needed. Recombinant immunotoxins (RITs) are chimeric proteins that are composed of the Fv or Fab portion of an antibody fused to a bacterial toxin. B-cell maturation a...
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| 發表在: | Antib Ther |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6157621/ https://ncbi.nlm.nih.gov/pubmed/30272049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tby004 |
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