Preclinical development of anti-BCMA immunotoxins targeting multiple myeloma

BACKGROUND: Multiple myeloma (MM) is a B-cell malignancy that is incurable for the majority of patients. New treatments are urgently needed. Recombinant immunotoxins (RITs) are chimeric proteins that are composed of the Fv or Fab portion of an antibody fused to a bacterial toxin. B-cell maturation a...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Antib Ther
Asıl Yazarlar: Shancer, Zoe, Williams, Matthew, Igelman, Austin, Nagata, Satoshi, Ise, Tomoko, Pastan, Ira, Bera, Tapan K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
Konular:
Research article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6157621/
https://ncbi.nlm.nih.gov/pubmed/30272049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tby004
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