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Preclinical development of anti-BCMA immunotoxins targeting multiple myeloma
BACKGROUND: Multiple myeloma (MM) is a B-cell malignancy that is incurable for the majority of patients. New treatments are urgently needed. Recombinant immunotoxins (RITs) are chimeric proteins that are composed of the Fv or Fab portion of an antibody fused to a bacterial toxin. B-cell maturation a...
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| Publicado no: | Antib Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6157621/ https://ncbi.nlm.nih.gov/pubmed/30272049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abt/tby004 |
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