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Pivotal role for α(V) integrins in sustained Tfh support of the germinal center response for long-lived plasma cell generation
CD4+ follicular helper T cells (Tfh) are essential for germinal center (GC) reactions in the lymph node that generate high-affinity, long-lived plasma cells (LLPCs). Temporal GC analysis suggests B memory cells (Bmem) are generated early, while LLPCs are generated late in the GC reaction. Distinct r...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6410787/ https://ncbi.nlm.nih.gov/pubmed/30770452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809329116 |
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