Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ

Type II IFN (IFN-γ) is a proinflammatory T lymphocyte cytokine that serves in priming of microglia—resident CNS macrophages—during the complex microglial activation process under pathological conditions. Priming generally permits an exaggerated microglial response to a secondary inflammatory stimulu...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ta, Thuy-Truc, Dikmen, Hasan Onur, Schilling, Simone, Chausse, Bruno, Lewen, Andrea, Hollnagel, Jan-Oliver, Kann, Oliver
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410786/
https://ncbi.nlm.nih.gov/pubmed/30782788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813562116
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