Filovirus Virulence in Interferon α/β and γ Double Knockout Mice, and Treatment with Favipiravir

The 2014 Ebolavirus outbreak in West Africa highlighted the need for vaccines and therapeutics to prevent and treat filovirus infections. A well-characterized small animal model that is susceptible to wild-type filoviruses would facilitate the screening of anti-filovirus agents. To that end, we char...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Comer, Jason E., Escaffre, Olivier, Neef, Natasha, Brasel, Trevor, Juelich, Terry L., Smith, Jennifer K., Smith, Jeanon, Kalveram, Birte, Perez, David D., Massey, Shane, Zhang, Lihong, Freiberg, Alexander N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410141/
https://ncbi.nlm.nih.gov/pubmed/30717492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11020137
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