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Natural History and Pathogenesis of Wild-Type Marburg Virus Infection in STAT2 Knockout Hamsters

Marburg virus (MARV; family Filoviridae) causes sporadic outbreaks of Marburg hemorrhagic fever in sub-Saharan Africa with case fatality rates reaching 90%. Wild-type filoviruses, including MARV and the closely related Ebola virus, are unable to suppress the type I interferon response in rodents, an...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Atkins, Colm, Miao, Jinxin, Kalveram, Birte, Juelich, Terry, Smith, Jennifer K, Perez, David, Zhang, Lihong, Westover, Jonna L B, Van Wettere, Arnaud J, Gowen, Brian B, Wang, Zhongde, Freiberg, Alexander N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249581/
https://ncbi.nlm.nih.gov/pubmed/30192975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy457
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