Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever

BACKGROUND: Junín virus (JUNV), the etiologic agent of Argentine hemorrhagic fever (AHF), is classified by the NIAID and CDC as a Category A priority pathogen. Presently, antiviral therapy for AHF is limited to immune plasma, which is readily available only in the endemic regions of Argentina. T-705...

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Autori principali: Gowen, Brian B., Juelich, Terry L., Sefing, Eric J., Brasel, Trevor, Smith, Jennifer K., Zhang, Lihong, Tigabu, Bersabeh, Hill, Terence E., Yun, Tatyana, Pietzsch, Colette, Furuta, Yousuke, Freiberg, Alexander N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873268/
https://ncbi.nlm.nih.gov/pubmed/24386500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002614
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