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Mechanisms of Strain Diversity of Disease-Associated in-Register Parallel β-Sheet Amyloids and Implications About Prion Strains

The mechanism of prion strain diversity remains unsolved. Investigation of inheritance and diversification of protein-based pathogenic information demands the identification of the detailed structures of abnormal isoforms of the prion protein (PrP(Sc)); however, achieving purification is difficult w...

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Bibliografski detalji
Izdano u:Viruses
Glavni autori: Taguchi, Yuzuru, Otaki, Hiroki, Nishida, Noriyuki
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410106/
https://ncbi.nlm.nih.gov/pubmed/30696005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11020110
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