Llwytho...
Chlorambucil Conjugated Ugi Dendrimers with PAMAM-NH(2) Core and Evaluation of Their Anticancer Activity
Herein, a new Ugi multicomponent reaction strategy is described to enhance activity and solubility of the chemotherapeutic drug chlorambucil through its conjugation to poly(amidoamine) (PAMAM-NH(2)) dendrimers with the simultaneous introduction of lipidic (i-Pr) and cationic (–NH(2)) or anionic (–CO...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Pharmaceutics |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
MDPI
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6409784/ https://ncbi.nlm.nih.gov/pubmed/30717083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11020059 |
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