Wird geladen...
Chlorambucil Conjugated Ugi Dendrimers with PAMAM-NH(2) Core and Evaluation of Their Anticancer Activity
Herein, a new Ugi multicomponent reaction strategy is described to enhance activity and solubility of the chemotherapeutic drug chlorambucil through its conjugation to poly(amidoamine) (PAMAM-NH(2)) dendrimers with the simultaneous introduction of lipidic (i-Pr) and cationic (–NH(2)) or anionic (–CO...
Gespeichert in:
| Veröffentlicht in: | Pharmaceutics |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2019
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6409784/ https://ncbi.nlm.nih.gov/pubmed/30717083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11020059 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|