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A Noninvasive Comparison Study between Human Gliomas with IDH1 and IDH2 Mutations by MR Spectroscopy

The oncogenes that are expressed in gliomas reprogram particular pathways of glucose, amino acids, and fatty acid metabolism. Mutations in isocitrate dehydrogenase genes (IDH1/2) in diffuse gliomas are associated with abnormally high levels of 2-hydroxyglutarate (2-HG) levels. The aim of this study...

詳細記述

保存先:
書誌詳細
出版年:Metabolites
主要な著者: Shen, Xin, Voets, Natalie L., Larkin, Sarah J., de Pennington, Nick, Plaha, Puneet, Stacey, Richard, McCullagh, James S. O., Schofield, Christopher J., Clare, Stuart, Jezzard, Peter, Cadoux-Hudson, Tom, Ansorge, Olaf, Emir, Uzay E.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409728/
https://ncbi.nlm.nih.gov/pubmed/30791611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9020035
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