A Noninvasive Comparison Study between Human Gliomas with IDH1 and IDH2 Mutations by MR Spectroscopy

The oncogenes that are expressed in gliomas reprogram particular pathways of glucose, amino acids, and fatty acid metabolism. Mutations in isocitrate dehydrogenase genes (IDH1/2) in diffuse gliomas are associated with abnormally high levels of 2-hydroxyglutarate (2-HG) levels. The aim of this study...

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Detalhes bibliográficos
Publicado no:Metabolites
Main Authors: Shen, Xin, Voets, Natalie L., Larkin, Sarah J., de Pennington, Nick, Plaha, Puneet, Stacey, Richard, McCullagh, James S. O., Schofield, Christopher J., Clare, Stuart, Jezzard, Peter, Cadoux-Hudson, Tom, Ansorge, Olaf, Emir, Uzay E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409728/
https://ncbi.nlm.nih.gov/pubmed/30791611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9020035
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