Improved Dissolution and Oral Bioavailability of Valsartan Using a Solidified Supersaturable Self-Microemulsifying Drug Delivery System Containing Gelucire(®) 44/14

To improve the dissolution and oral bioavailability of valsartan (VST), we previously formulated a supersaturable self-microemulsifying drug delivery system (SuSMED) composed of Capmul(®) MCM (oil), Tween(®) 80 (surfactant), Transcutol(®) P (cosurfactant), and Poloxamer 407 (precipitation inhibitor)...

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Vydáno v:Pharmaceutics
Hlavní autoři: Shin, Dong Jun, Chae, Bo Ram, Goo, Yoon Tae, Yoon, Ho Yub, Kim, Chang Hyun, Sohn, Se Il, Oh, Dongho, Lee, Ahram, Song, Seh Hyon, Choi, Young Wook
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409713/
https://ncbi.nlm.nih.gov/pubmed/30708963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11020058
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