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Dual Inhibition of GSK3β and CDK5 Protects the Cytoskeleton of Neurons from Neuroinflammatory-Mediated Degeneration In Vitro and In Vivo
Neuroinflammation is a hallmark of neurological disorders and is accompanied by the production of neurotoxic agents such as nitric oxide. We used stem cell-based phenotypic screening and identified small molecules that directly protected neurons from neuroinflammation-induced degeneration. We demons...
Zapisane w:
| Wydane w: | Stem Cell Reports |
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6409486/ https://ncbi.nlm.nih.gov/pubmed/30773488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.01.015 |
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