Structure-Based Peptide Inhibitor Design of Amyloid-β Aggregation

Many human neurodegenerative diseases are associated with amyloid fibril formation. Inhibition of amyloid formation is of importance for therapeutics of the related diseases. However, the development of selective potent amyloid inhibitors remains challenging. Here based on the structures of amyloid...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Lu, Jinxia, Cao, Qin, Wang, Chuchu, Zheng, Jing, Luo, Feng, Xie, Jingfei, Li, Yichen, Ma, Xiaojuan, He, Lin, Eisenberg, David, Nowick, James, Jiang, Lin, Li, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409328/
https://ncbi.nlm.nih.gov/pubmed/30886570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00054
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