PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications

Tumor progression through immune evasion is a major challenge in cancer therapy. Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more...

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Publicat a:J Oncol
Autors principals: Darvin, Pramod, Sasidharan Nair, Varun, Elkord, Eyad
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409026/
https://ncbi.nlm.nih.gov/pubmed/30915120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3958908
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