Caricamento...

DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer

BACKGROUND: Colorectal cancer (CRC) is the third most commonly diagnosed human malignancy worldwide. Upregulation of inhibitory immune checkpoints by tumor-infiltrating immune cells (TIICs) or their ligands by tumor cells leads to tumor evasion from host immunosurveillance. Changes in DNA methylatio...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Sasidharan Nair, Varun, Toor, Salman M., Taha, Rowaida Z., Shaath, Hibah, Elkord, Eyad
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080402/
https://ncbi.nlm.nih.gov/pubmed/30081950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0539-3
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !