تحميل...
DNA methylation and repressive H3K9 and H3K27 trimethylation in the promoter regions of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, and PD-L1 genes in human primary breast cancer
BACKGROUND: High expression of immune checkpoints in tumor microenvironment plays significant roles in inhibiting anti-tumor immunity, which is associated with poor prognosis and cancer progression. Major epigenetic modifications in both DNA and histone could be involved in upregulation of immune ch...
محفوظ في:
| الحاوية / القاعدة: | Clin Epigenetics |
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| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
BioMed Central
2018
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6003083/ https://ncbi.nlm.nih.gov/pubmed/29983831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0512-1 |
| الوسوم: |
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