Chargement en cours...
Catalytic Asymmetric Synthesis of Trifluoromethylated γ-Amino Acids via Umpolung Addition of Trifluoromethyl Imines to Carboxylic Acid Derivatives
Enabled by the discovery of novel cinchona alkaloid-derived chiral phase-transfer catalysts, highly chemo-, regio-, diastereo- and enantioselective umpolung additions of trifluoromethyl imines to α, β-unsaturated N-acylpyrroles were realized. With a catalyst loading ranging from 0.2 to 5.0 mol%, thi...
Enregistré dans:
| Publié dans: | Angew Chem Int Ed Engl |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6408948/ https://ncbi.nlm.nih.gov/pubmed/29232488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201710915 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|