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RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones

We show that transcription induced by nuclear receptors for estrogen (E(2)) or retinoic acid (RA) is associated with formation of chromatin loops that juxtapose the 5’ end (containing the promoter) with the enhancer and the 3′ polyA addition site of the target gene. We find three loop configurations...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Pezone, Antonio, Zuchegna, Candida, Tramontano, Alfonso, Romano, Antonella, Russo, Giusi, de Rosa, Mariarosaria, Vinciguerra, Maria, Porcellini, Antonio, Gottesman, Max E., Avvedimento, Enrico Vittorio
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408484/
https://ncbi.nlm.nih.gov/pubmed/30850627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40123-6
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