Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae

Evolutionarily conserved virulence factors can be candidate therapeutic targets or vaccine antigens. Here, we investigated the evolutionary selective pressures on 16 pneumococcal choline-binding cell-surface proteins since Streptococcus pneumoniae is one of the pathogens posing the greatest threats...

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Pubblicato in:Commun Biol
Autori principali: Yamaguchi, Masaya, Goto, Kana, Hirose, Yujiro, Yamaguchi, Yuka, Sumitomo, Tomoko, Nakata, Masanobu, Nakano, Kazuhiko, Kawabata, Shigetada
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408437/
https://ncbi.nlm.nih.gov/pubmed/30886906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0340-7
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