Evolutionary inactivation of a sialidase in group B Streptococcus

Group B Streptococcus (GBS) is a leading cause of bacterial sepsis and meningitis in newborns. GBS possesses a protein with homology to the pneumococcal virulence factor, NanA, which has neuraminidase (sialidase) activity and promotes blood-brain barrier penetration. However, phylogenetic sequence a...

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Pubblicato in:Sci Rep
Autori principali: Yamaguchi, Masaya, Hirose, Yujiro, Nakata, Masanobu, Uchiyama, Satoshi, Yamaguchi, Yuka, Goto, Kana, Sumitomo, Tomoko, Lewis, Amanda L., Kawabata, Shigetada, Nizet, Victor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926279/
https://ncbi.nlm.nih.gov/pubmed/27352769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28852
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