Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae

Evolutionarily conserved virulence factors can be candidate therapeutic targets or vaccine antigens. Here, we investigated the evolutionary selective pressures on 16 pneumococcal choline-binding cell-surface proteins since Streptococcus pneumoniae is one of the pathogens posing the greatest threats...

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Bibliographic Details
Published in:Commun Biol
Main Authors: Yamaguchi, Masaya, Goto, Kana, Hirose, Yujiro, Yamaguchi, Yuka, Sumitomo, Tomoko, Nakata, Masanobu, Nakano, Kazuhiko, Kawabata, Shigetada
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408437/
https://ncbi.nlm.nih.gov/pubmed/30886906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0340-7
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