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Identification of evolutionarily conserved virulence factor by selective pressure analysis of Streptococcus pneumoniae

Evolutionarily conserved virulence factors can be candidate therapeutic targets or vaccine antigens. Here, we investigated the evolutionary selective pressures on 16 pneumococcal choline-binding cell-surface proteins since Streptococcus pneumoniae is one of the pathogens posing the greatest threats...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Yamaguchi, Masaya, Goto, Kana, Hirose, Yujiro, Yamaguchi, Yuka, Sumitomo, Tomoko, Nakata, Masanobu, Nakano, Kazuhiko, Kawabata, Shigetada
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408437/
https://ncbi.nlm.nih.gov/pubmed/30886906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0340-7
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