The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer

Pancreatic cancer, mostly pancreatic ductal adenocarcinomas (PDAC), is one of the most lethal cancers, with a dismal median survival around 8 months. PDAC is notoriously resistant to chemotherapy. Thus far, numerous attempts using novel targeted therapies and immunotherapies yielded limited clinical...

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Bibliographic Details
Published in:Oncogene
Main Authors: Jia, Yanfei, Gu, Dongsheng, Wan, Jun, Yu, Beiqin, Zhang, Xiaoli, Chiorean, E. Gabriela, Wang, Yunshan, Xie, Jingwu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408295/
https://ncbi.nlm.nih.gov/pubmed/30382189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0553-0
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