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Role of fatty acid synthase in gemcitabine and radiation resistance of pancreatic cancers

Human fatty acid synthase (FASN) is a homo-dimeric protein with multi-enzymatic activity responsible for the synthesis of palmitate. FASN expression has been found to be up-regulated in multiple types of human cancers and its expression correlates with poor prognosis possibly by causing treatment re...

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Detalhes bibliográficos
Main Authors: Yang, Youyun, Li, Hailan, Li, Zhaomin, Zhao, Zijin, Yip-Schneider, Michelle, Fan, Qipeng, Schmidt, C. Max, Chiorean, E. Gabriela, Xie, Jingwu, Cheng, Liang, Chen, Jey-Hsin, Zhang, Jian-Ting
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039422/
https://ncbi.nlm.nih.gov/pubmed/21331354
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