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The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer
Pancreatic cancer, mostly pancreatic ductal adenocarcinomas (PDAC), is one of the most lethal cancers, with a dismal median survival around 8 months. PDAC is notoriously resistant to chemotherapy. Thus far, numerous attempts using novel targeted therapies and immunotherapies yielded limited clinical...
Gespeichert in:
| Veröffentlicht in: | Oncogene |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6408295/ https://ncbi.nlm.nih.gov/pubmed/30382189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0553-0 |
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