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Role of mGlu2 in the 5-HT(2A) receptor-dependent antipsychotic activity of clozapine in mice
BACKGROUND: Serotonin 5-HT(2A) and metabotropic glutamate 2 (mGlu2) are neurotransmitter G protein-coupled receptors (GPCRs) involved in the signaling mechanisms underlying psychosis and schizophrenia treatment. Previous findings in mGlu2 knockout (KO) mice suggested that mGlu2 is necessary for head...
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| Publicado no: | Psychopharmacology (Berl) |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6408231/ https://ncbi.nlm.nih.gov/pubmed/30209534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-018-5015-4 |
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