Differences in 5-HT2A and mGlu2 Receptor Expression Levels and Repressive Epigenetic Modifications at the 5-HT2A Promoter Region in the Roman Low- (RLA-I) and High- (RHA-I) Avoidance Rat Strains

The serotonin 2A (5-HT(2A)) and metabotropic glutamate 2 (mGlu2) receptors regulate each other and are associated with schizophrenia. The Roman high- (RHA-I) and the Roman low- (RLA-I) avoidance rat strains present well-differentiated behavioral profiles, with the RHA-I strain emerging as a putative...

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Veröffentlicht in:Mol Neurobiol
Hauptverfasser: Fomsgaard, Luna, Moreno, Jose L., de la Fuente Revenga, Mario, Brudek, Tomasz, Adamsen, Dea, Rio-Alamos, Cristobal, Saunders, Justin, Klein, Anders Bue, Oliveras, Ignasi, Cañete, Toni, Blazquez, Gloria, Tobeña, Adolf, Fernandez-Teruel, Albert, Gonzalez-Maeso, Javier, Aznar, Susana
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587367/
https://ncbi.nlm.nih.gov/pubmed/28265857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-017-0457-y
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