Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

Research on age-related regenerative failure of skeletal muscle has extensively focused on the phenotypes of muscle stem cells (MuSCs). In contrast, the impact of aging on regulatory cells in the MuSC niche remains largely unexplored. Here, we demonstrate that aging impairs the function of mouse fib...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Cell Stem Cell
Κύριοι συγγραφείς: Lukjanenko, Laura, Karaz, Sonia, Stuelsatz, Pascal, Gurriaran-Rodriguez, Uxia, Michaud, Joris, Dammone, Gabriele, Sizzano, Federico, Mashinchian, Omid, Ancel, Sara, Migliavacca, Eugenia, Liot, Sophie, Jacot, Guillaume, Metairon, Sylviane, Raymond, Frederic, Descombes, Patrick, Palini, Alessio, Chazaud, Benedicte, Rudnicki, Michael A., Bentzinger, C. Florian, Feige, Jerome N.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2019
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408230/
https://ncbi.nlm.nih.gov/pubmed/30686765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.12.014
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