Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

Research on age-related regenerative failure of skeletal muscle has extensively focused on the phenotypes of muscle stem cells (MuSCs). In contrast, the impact of aging on regulatory cells in the MuSC niche remains largely unexplored. Here, we demonstrate that aging impairs the function of mouse fib...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Stem Cell
Egile Nagusiak: Lukjanenko, Laura, Karaz, Sonia, Stuelsatz, Pascal, Gurriaran-Rodriguez, Uxia, Michaud, Joris, Dammone, Gabriele, Sizzano, Federico, Mashinchian, Omid, Ancel, Sara, Migliavacca, Eugenia, Liot, Sophie, Jacot, Guillaume, Metairon, Sylviane, Raymond, Frederic, Descombes, Patrick, Palini, Alessio, Chazaud, Benedicte, Rudnicki, Michael A., Bentzinger, C. Florian, Feige, Jerome N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408230/
https://ncbi.nlm.nih.gov/pubmed/30686765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2018.12.014
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