Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response

RATIONALE: Secreted and membrane-bound proteins, which account for 1/3 of all proteins, play critical roles in heart health and disease. The endoplasmic reticulum (ER) is the site for synthesis, folding, and quality control of these proteins. Loss of ER homeostasis and function underlies the pathoge...

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Опубликовано в: :Circ Res
Главные авторы: Binder, Pablo, Wang, Shunyao, Radu, Maria, Zin, Min, Collins, Lucy, Khan, Saba, Li, Yatong, Sekeres, Karolina, Humphreys, Neil, Swanton, Eileithyia, Reid, Adam, Pu, Fay, Oceandy, Delvac, Guan, Kaomei, Hille, Susanne S., Frey, Norbert, Müller, Oliver J., Cartwright, Elizabeth J., Chernoff, Jonathan, Wang, Xin, Liu, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: Lippincott Williams & Wilkins 2019
Предметы:
Cellular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407830/
https://ncbi.nlm.nih.gov/pubmed/30620686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.312829
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