Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response

RATIONALE: Secreted and membrane-bound proteins, which account for 1/3 of all proteins, play critical roles in heart health and disease. The endoplasmic reticulum (ER) is the site for synthesis, folding, and quality control of these proteins. Loss of ER homeostasis and function underlies the pathoge...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Binder, Pablo, Wang, Shunyao, Radu, Maria, Zin, Min, Collins, Lucy, Khan, Saba, Li, Yatong, Sekeres, Karolina, Humphreys, Neil, Swanton, Eileithyia, Reid, Adam, Pu, Fay, Oceandy, Delvac, Guan, Kaomei, Hille, Susanne S., Frey, Norbert, Müller, Oliver J., Cartwright, Elizabeth J., Chernoff, Jonathan, Wang, Xin, Liu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2019
Assuntos:
Cellular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407830/
https://ncbi.nlm.nih.gov/pubmed/30620686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.118.312829
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