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PI3k and Stat3: Oncogenes that are Required for Gap Junctional, Intercellular Communication

Gap junctional, intercellular communication (GJIC) is interrupted in cells transformed by oncogenes such as activated Src. The Src effector, Ras, is required for this effect, so that Ras inhibition restores GJIC in Src-transformed cells. Interestingly, the inhibition of the Src effector phosphatidyl...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Geletu, Mulu, Taha, Zaid, Gunning, Patrick T., Raptis, Leda
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406562/
https://ncbi.nlm.nih.gov/pubmed/30717267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11020167
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