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A Biophysical Approach to the Identification of Novel ApoE Chemical Probes

Alzheimer’s disease (AD) is the most common type of dementia and, after age, the greatest risk factor for developing AD is the allelic variation of apolipoprotein E (ApoE), with homozygote carriers of the ApoE4 allele having an up to 12-fold greater risk of developing AD than noncarriers. Apolipopro...

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Publicat a:Biomolecules
Autors principals: Kraft, Lucas, Serpell, Louise C., Atack, John R.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406525/
https://ncbi.nlm.nih.gov/pubmed/30700058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9020048
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