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A Biophysical Approach to the Identification of Novel ApoE Chemical Probes

Alzheimer’s disease (AD) is the most common type of dementia and, after age, the greatest risk factor for developing AD is the allelic variation of apolipoprotein E (ApoE), with homozygote carriers of the ApoE4 allele having an up to 12-fold greater risk of developing AD than noncarriers. Apolipopro...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Kraft, Lucas, Serpell, Louise C., Atack, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406525/
https://ncbi.nlm.nih.gov/pubmed/30700058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9020048
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