Decreased Lung Tumor Development in SwAPP Mice through the Downregulation of CHI3L1 and STAT 3 Activity via the Upregulation of miRNA342-3p

We previously found that lung tumor development was reduced in a presenilin (PS) Alzheimer’s disease (AD) mouse model. Here, we investigated whether this reducing effect could occur in a different AD mouse model. We investigated urethane-induced (1 mg/g) lung tumor development and melanoma growth in...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Lee, Dong Hun, Kim, Ki Cheon, Hwang, Chul Ju, Park, Kyung Ran, Jung, Young Suk, Kim, Sun Young, Kim, Ji Young, Song, Ju Kyung, Song, Min Ji, Choi, Min Ki, Hwang, Dae Youn, Han, Sang-Bae, Hong, Jin Tae
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406047/
https://ncbi.nlm.nih.gov/pubmed/30849743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.02.007
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