Decreased Lung Tumor Development in SwAPP Mice through the Downregulation of CHI3L1 and STAT 3 Activity via the Upregulation of miRNA342-3p

We previously found that lung tumor development was reduced in a presenilin (PS) Alzheimer’s disease (AD) mouse model. Here, we investigated whether this reducing effect could occur in a different AD mouse model. We investigated urethane-induced (1 mg/g) lung tumor development and melanoma growth in...

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Udgivet i:Mol Ther Nucleic Acids
Main Authors: Lee, Dong Hun, Kim, Ki Cheon, Hwang, Chul Ju, Park, Kyung Ran, Jung, Young Suk, Kim, Sun Young, Kim, Ji Young, Song, Ju Kyung, Song, Min Ji, Choi, Min Ki, Hwang, Dae Youn, Han, Sang-Bae, Hong, Jin Tae
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6406047/
https://ncbi.nlm.nih.gov/pubmed/30849743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.02.007
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