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Inhibition of invasive pancreatic cancer: restoring cell apoptosis by activating mitochondrial p53

Pancreatic ductal adenocarcinoma (PDAC), constitutes >90% of pancreatic cancers (PC) and is one of the most aggressive human tumors. Standard chemotherapies for PDAC (e.g., gemcitabine, FOLFIRINOX, etc.) has proven to be largely ineffective. Herein, we report a novel molecule (i.e., compound 1) t...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Cheng, Jiongjia, Okolotowicz, Karl J, Ryan, Daniel, Mose, Evangeline, Lowy, Andrew M, Cashman, John R
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405982/
https://ncbi.nlm.nih.gov/pubmed/30906636
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