Elevated Wall Tension Leads to Reduced miR‐133a in the Thoracic Aorta by Exosome Release

BACKGROUND: Reduced miR‐133a was previously found to be associated with thoracic aortic (TA) dilation, as seen in aneurysm disease. Because wall tension increases with vessel diameter (Law of Laplace), this study tested the hypothesis that elevated tension led to the reduction of miR‐133a in the TA....

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Detaylı Bibliyografya
Yayımlandı:J Am Heart Assoc
Asıl Yazarlar: Akerman, Adam W., Blanding, Walker M., Stroud, Robert E., Nadeau, Elizabeth K., Mukherjee, Rupak, Ruddy, Jean Marie, Zile, Michael R., Ikonomidis, John S., Jones, Jeffrey A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405702/
https://ncbi.nlm.nih.gov/pubmed/30572760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010332
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