Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity

Leukemia, specifically acute myeloid leukemia (AML), is a common malignancy that can be differentiated into multiple subtypes based on leukemogenic history and etiology. Although genetic aberrations, particularly cytogenetic abnormalities and mutations in known oncogenes, play an integral role in AM...

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Detalles Bibliográficos
Publicado en:Front Genet
Autores principales: Goldman, Samantha L., Hassan, Ciaran, Khunte, Mihir, Soldatenko, Arielle, Jong, Yunji, Afshinnekoo, Ebrahim, Mason, Christopher E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405641/
https://ncbi.nlm.nih.gov/pubmed/30881380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00133
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