Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity

Leukemia, specifically acute myeloid leukemia (AML), is a common malignancy that can be differentiated into multiple subtypes based on leukemogenic history and etiology. Although genetic aberrations, particularly cytogenetic abnormalities and mutations in known oncogenes, play an integral role in AM...

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Bibliographic Details
Published in:Front Genet
Main Authors: Goldman, Samantha L., Hassan, Ciaran, Khunte, Mihir, Soldatenko, Arielle, Jong, Yunji, Afshinnekoo, Ebrahim, Mason, Christopher E.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405641/
https://ncbi.nlm.nih.gov/pubmed/30881380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00133
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