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Epigenetic Modifications in Acute Myeloid Leukemia: Prognosis, Treatment, and Heterogeneity

Leukemia, specifically acute myeloid leukemia (AML), is a common malignancy that can be differentiated into multiple subtypes based on leukemogenic history and etiology. Although genetic aberrations, particularly cytogenetic abnormalities and mutations in known oncogenes, play an integral role in AM...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Goldman, Samantha L., Hassan, Ciaran, Khunte, Mihir, Soldatenko, Arielle, Jong, Yunji, Afshinnekoo, Ebrahim, Mason, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405641/
https://ncbi.nlm.nih.gov/pubmed/30881380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00133
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