Edition of TFAM gene by CRISPR/Cas9 technology in bovine model

The mitochondrial transcription factor A (TFAM) is a mitochondrial DNA (mtDNA) binding protein essential for the initiation of transcription and genome maintenance. Recently it was demonstrated that the primary role of TFAM is to maintain the integrity of mtDNA and that it is a key regulator of mtDN...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: de Oliveira, Vanessa Cristina, Moreira, Gabriel Sassarão Alves, Bressan, Fabiana Fernandes, Gomes Mariano Junior, Clésio, Roballo, Kelly Cristine Santos, Charpentier, Marine, Concordet, Jean-Paul, Meirelles, Flávio Vieira, Ambrósio, Carlos Eduardo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405117/
https://ncbi.nlm.nih.gov/pubmed/30845180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213376
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