Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration

Staphylococcus aureus Panton-Valentine leukocidin is a pore-forming toxin targeting the human C5a receptor (hC5aR), enabling this pathogen to battle the immune response by destroying phagocytes through targeted lysis. The mechanisms that contribute to rapid cell lysis are largely unexplored. Here, w...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FASEB J
Main Authors: Haapasalo, Karita, Wollman, Adam J. M., de Haas, Carla J. C., van Kessel, Kok P. M., van Strijp, Jos A. G., Leake, Mark C.
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404581/
https://ncbi.nlm.nih.gov/pubmed/30509126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801910R
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