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Novel compounds that specifically bind and modulate MscL: insights into channel gating mechanisms
The bacterial mechanosensitive channel of large conductance (MscL) normally functions as an emergency release valve discharging cytoplasmic solutes upon osmotic stress. Opening the large pore of MscL inappropriately is detrimental to the cell, and thus it has been speculated to be a potential antibi...
Kaydedildi:
| Yayımlandı: | FASEB J |
|---|---|
| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Federation of American Societies for Experimental Biology
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404570/ https://ncbi.nlm.nih.gov/pubmed/30359098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801628R |
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