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Sphingosine kinase 2 promotes lipotoxicity in pancreatic β-cells and the progression of diabetes
Loss of functional β-cell mass caused by lipotoxicity is a key pathogenic factor in the development of type 2 diabetes mellitus (T2DM). We have previously reported that sphingosine kinase (SK)1 is an endogenous protector of β-cells against lipotoxicity. The current study reports that SK2, another is...
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| Publicado no: | FASEB J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404568/ https://ncbi.nlm.nih.gov/pubmed/30452878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801496R |
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