Proproliferative function of adaptor protein GRB10 in prostate carcinoma

Growth factor receptor–binding protein 10 (GRB10) is a well-known adaptor protein and a recently identified substrate of the mammalian target of rapamycin (mTOR). Depletion of GRB10 increases insulin sensitivity and overexpression suppresses PI3K/Akt signaling. Because the major reason for the limit...

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Veröffentlicht in:FASEB J
Hauptverfasser: Khan, Mohammad Imran, Al Johani, Ahmed, Hamid, Abid, Ateeq, Bushra, Manzar, Nishat, Adhami, Vaqar Mustafa, Lall, Rahul K., Rath, Suvasmita, Sechi, Mario, Siddiqui, Imtiaz Ahmad, Choudhry, Hani, Zamzami, Mazin A., Havighurst, Thomas C., Huang, Wei, Ntambi, James M., Mukhtar, Hasan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404554/
https://ncbi.nlm.nih.gov/pubmed/30379590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800265RR
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