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Human three-dimensional in vitro model of hepatic zonation to predict zonal hepatotoxicity

BACKGROUND: Various hepatic models mimicking liver lobules have been investigated to evaluate the potential hepatotoxic effects of chemicals and drugs, but in vitro hepatic models of zonal hepatotoxicity have not yet been established. Herein, we developed a three-dimensional (3D) hepatic zonal chann...

詳細記述

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書誌詳細
出版年:J Biol Eng
主要な著者: Ahn, Jaehwan, Ahn, Jun-Ho, Yoon, Seokjoo, Nam, Yoon Sung, Son, Mi-Young, Oh, Jung-Hwa
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404355/
https://ncbi.nlm.nih.gov/pubmed/30886645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0148-5
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