Human three-dimensional in vitro model of hepatic zonation to predict zonal hepatotoxicity

BACKGROUND: Various hepatic models mimicking liver lobules have been investigated to evaluate the potential hepatotoxic effects of chemicals and drugs, but in vitro hepatic models of zonal hepatotoxicity have not yet been established. Herein, we developed a three-dimensional (3D) hepatic zonal chann...

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Dades bibliogràfiques
Publicat a:J Biol Eng
Autors principals: Ahn, Jaehwan, Ahn, Jun-Ho, Yoon, Seokjoo, Nam, Yoon Sung, Son, Mi-Young, Oh, Jung-Hwa
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404355/
https://ncbi.nlm.nih.gov/pubmed/30886645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0148-5
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